Today humans rely entirely on technology for their subsistence, and the interaction between technology and biology has played a key role in human evolution. How exactly technology has shaped our biological and cultural evolution is one of paleoanthropology's major research questions.

 The African Paleosciences Laboratory use stone tool evidence to study the behavioral, cognitive, and biological bases of ancient technology in order to understand human evolutionary history and behavioral variability. 

The lab’s research focuses mainly on southern African stone tool technologies, using a combination of lithic analysis of archaeological specimens, experimental production of stone tools, and measurements of neurological, motor action, and social learning related to stone toolmaking.